Phytochemical screening by FTIR spectroscopic analysis of leaf extracts of Monotheca Buxifolia

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Dr. Faisal Nawaz
Shahzad Ahmad
Shazia Naheed
Zaheer Ahmad
Tahir Mehmmod

Abstract

This study is aimed to analyze the extracts n-hexane, toluene, chloroform, carbontetra chloride, butanol, methanol by keeping in view the pharmacological importance of the leaves of Monotheca buxifolia A. DC. Fourier transform infrared (FTIR) spectroscopic studies concludes that the peak value characteristic indicate the presence of several functional groups of important bioactive compounds in the extracts. The FTIR analysis of M. buxifolia conforms the presence of amides, alcohols, phenols, alkanes, ketones, aldehydes, aromatic compounds and carboxylic acids using the peaks values of functional groups. The results of current study are produced by FTIR spectrum supporting the medicinal importance of plants such as M. buxifolia that is used as a source for folk medicine.

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How to Cite
Nawaz, D. F., Ahmad, S., Naheed, S., Ahmad, Z., & Mehmmod, T. (2019). Phytochemical screening by FTIR spectroscopic analysis of leaf extracts of Monotheca Buxifolia. University of Wah Journal of Science and Technology (UWJST), 3, 15-22. Retrieved from http://uwjst.org.pk/index.php/uwjst/article/view/19
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References

[1] A. Sofowora. Medicinal Plants and Traditional Medicine in Africa, Karthala, Spectrum Publisher, 2002.
[2] D. J. Ashley. Colonic cancer arising in polyposis coli, Journal of Medical Genetics, Vol 6(4), pp. 376, 1969.
[3] A. Jemal, Ram C. Tiwari, T. Murray et al. Cancer Statistics, 2004. CA: A Cancer Journal for Clinicians, Vol. 54(1), pp. 8-29, 2004.
[4] A. Iqbal, and F. Aqil. In vitro efficacy of bioactive extracts of 15 medicinal plants against ESβL-producing multidrug-resistant enteric bacteria, Microbiological Research, Vol. 162(3), pp. 264-275, 2007.
[5] P. G. Kareru, J. M. Keriko, A. N. Gachanja, and G. M. Kenji. Direct detection of triterpenoid saponins in medicinal plants, African Journal of Traditional, Complementary and Alternative medicines, Vol. 5(1), pp. 56-60, 2008.
[6] S. Muruganantham, G. Anbalagan and N. Ramamurthy. FT-IR and SEM-EDS comparative analysis of medicinal plants, Eclipta alba Hassk and Eclipta prostrata Linn, Romanian Journal of Biophysics, Vol. 19(4), pp. 285-294, 2009.
[7] N. Ramamurthy and S. Kannan. Fourier transform infrared spectroscopic analysis of a plant (Calotropis gigantea Linn) from an industrial village, Cuddalore dt, Tamilnadu, India. Romanian journal of Biophysics, Vol. 17(4), pp. 269-276, 2007.
[8] G. Kumar, L. Karthik and K. B. Rao. Phytochemical composition and in vitro antimicrobial activity of Bauhinia racemosa Lamk (Caesalpiniaceae), International Journal of Pharmaceutical Sciences and Research, Vol. 1(11), pp. 51, 2010.
[9] P. Ragavendran, D. Sophia, A. C. Raj amd V. K. Gopalakrishnan. Functional group analysis of various extracts of Aerva lanata by ftir spectrum. Pharmacologyonline, Vol. 1, pp. 358-364, 2011.
[10] T. Starlin, P. Ragavendran, C.A. Raj, P. C. Perumal and V. K. Gopalakrishnan. Element and functional group analysis of Ichnocarpus frutescens R. Br.(Apocynaceae). International Journal of Pharmacy and Pharmaceutical Science, Vol. 4, pp. 343-345, 2012. [11] R. Ashokkumar and M. Ramaswamy. Phytochemical screening by FTIR spectroscopic analysis of leaf extracts of selected Indian Medicinal plants, Journal of Current Microbiology and Applied Sciences, Vol. 3(1), pp. 395-406, 2014.
[12] J. Rehman, I. U. Khan, S. Farid, S. Kamal and N. Aslam. Phytochemical screening and evaluation of in-vitro antioxidant potential of Monotheca buxifolia, Journal of Biotechnol Pharmaceutical Research, Vol. 4(4), pp. 54-60, 2013.
[13] S. Jan, M. R. Khan, U. Rashid and J. Bokhari. Assessment of antioxidant potential, total phenolics and flavonoids of different solvent fractions of Monotheca buxifolia fruit. Osong public health and research perspectives, Vol. 4(5), pp. 246-254, 2013.
[14] S. Javed, I. E. Oise, L. Nahar, F. M. Ismail, Z. Mahmood and S. D. Sarker. Isolation, identification and antiproliferative activity of triterpenes from the genus Monotheca A. DC, Records of Natural Products, Vol. 10, pp. 782-787, 2016.
[15] A. N. Perveen and M. Qaiser. Pollen flora of Pakistan-XXXIV. Sapotaceae, Pakistan Journal of Botany, Vol. 34, pp. 225-228, 2002.
[16] K. Nasrullah, M. Ahmed, M. Wahab, M. Ajaib and S. S. Hussain. Studies along an altitudinal gradient in Monotheca buxifolia (falc.) ad, forest, District Lower Dir, Pakistan. Pakistan Journal of Botany, Vol. 42(5), pp. 3029-3038, 2010.
[17] I. Ullah, J. A. Khan, A. Adhikari and M. Shahid. Hepatoprotective effect of Monotheca buxifolia fruit against antitubercular drugs-induced hepatotoxicity in rats, Bangladesh Journal of Pharmacology, Vol. 11(1), pp. 248-56, 2016.
[18] A. Hazrat, M. Nisar and S. Zaman. Antibacterial activities of sixteen species of medicinal plants reported from Dir Kohistan Valley KPK, Pakistan, Pakistan Journal of Botany, Vol. 45(4), pp. 1369-1374, 2013.
[19] I. Ullah, J. A. Khan, A. Adhikari, A. Khan, P. A. Hannan, A. Wadood and U. Farooq. Bioassay-guided isolation of new urease inhibitory constituents from Monotheca buxifolia (Falc.) fruit and their molecular docking studies, Records of Natural Products, Vol. 10(6), pp. 744, 2016.
[20] Jan, Shumaila, and M. R. Khan. Protective effects of Monotheca buxifolia fruit on renal toxicity induced by CCl 4 in rats. BMC complementary and alternative medicine, Vol. 16(1), pp. 289, 2016.
[21] I. Ullah, J. A. Khan, Z. Iqbal, P. A. Hannan, F. Nasir, S. Muhammad, S. Jahan, and M. Rehman. Chemical composition, anti-bacterial and cytotoxic potential of n-hexane soluble fraction of monotheca buxifolia (falc) A. dc. fruit, National Academy Science Letters, Vol. 40, pp. 405-408, 2017.
[22] I. Ullah, J. A. Khan, M. Shahid, A. Khan, A. Adhikari, P. A. Hannan, U. Farooq. Pharmacological screening of Monotheca buxifolia (Falc.) A. DC. for antinociceptive, anti-inflammatory and antipyretic activities, BMC Complementary and Alternative Medicine, Vol. 16(1), pp. 273, 2016.
[23] K. M. Ahmed, A. C. Rana, and V. K. Dixit. Calotropis Species (Ascelpediaceace) A Comprehensive Review. Pharmacognosy Magazine, Vol. 1(2), pp.48, 2005.